Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | BRD2 | P25440 | 2/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581226 | 0.85 | TLR9 (0.38) | BRD4BRD2BRD3AURKBPOLB | |
| SCHEMBL28373125 | 0.83 | CYP1A2 (0.38) | LMNAKDM4ECYP3A4MAPTHPGD | |
| SCHEMBL28371735 | 0.82 | QDPR (0.34) | PDE10A | |
| SCHEMBL20581859 | 0.82 | SRD5A1 (0.47) | HPGDMEN1KMT2AHDAC6 | |
| SCHEMBL28885625 | 0.81 | KDM4E (0.38) | LMNAKDM4EMAPTPOLBAURKA | |
| SCHEMBL20581869 | 0.80 | ERN1 (0.39) | LMNAKDM4ECYP3A4MAPTHPGD | |
| SCHEMBL28376323 | 0.80 | CGAS (0.40) | LMNAKDM4ECYP3A4MAPTHPGD | |
| SCHEMBL28376695 | 0.80 | EGFR (0.39) | LMNAKDM4E | |
| SCHEMBL28371632 | 0.79 | DPP4 (0.35) | PDE3BPDE3APDE10ACYP1A2HSP90AA1 | |
| SCHEMBL28375857 | 0.77 | MAOA (0.39) | LMNAKDM4ECYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997671-A | Azaindole compounds as histone methyltransferase inhibitors | 全球血液疗法股份有限公司 | 2020-04-10 | — | — | CN | disclosed |