Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31732361 | 0.93 | PRKDC (0.56) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL27187284 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL31456012 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL13978005 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL29902518 | 0.80 | TRIM24 (0.45) | ALDH1A1TDP1PRKDCLMNAMAPT | |
| SCHEMBL28370226 | 0.80 | TRIM24 (0.45) | ALDH1A1TDP1PRKDCLMNAMAPT | |
| SCHEMBL10049625 | 0.80 | HTR2A (0.48) | PRKDCSMN1; SMN2L3MBTL1 | |
| SCHEMBL31456177 | 0.80 | PRKDC (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL31456113 | 0.78 | PRKDC (0.46) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL1539323 | 0.78 | ALDH1A1 (0.69) | ALDH1A1KDM4ETSHRTDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110937986-B | Compound synthesis method and application in field of insulin resistance improving medicines | 深圳市灵兰生物医药科技有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-110937987-B | Synthetic route of compound and application of compound in field of preparation of antidiabetic drugs | 深圳市灵兰生物医药科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-110937986-B | Compound synthesis method and application in field of insulin resistance improving medicines | 深圳市灵兰生物医药科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-110937987-A | Synthetic route of compound and application of compound in field of preparation of antidiabetic drugs | 深圳市灵兰生物医药科技有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-110937986-A | Compound synthesis method and application in field of insulin resistance improving medicines | 深圳市灵兰生物医药科技有限公司 | 2020-03-31 | — | — | CN | disclosed |