Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456177 | 0.91 | PRKDC (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL31456113 | 0.89 | PRKDC (0.46) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL31456110 | 0.88 | HTR2A (0.46) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL12831232 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL28375968 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL3469319 | 0.81 | HMGCR (0.60) | SMN1; SMN2HTR2AHMGCRTAAR1HTR2C | |
| SCHEMBL31455897 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL16018637 | 0.80 | PRKDC (0.56) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL24959989 | 0.79 | PRKDC (0.53) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL6375342 | 0.79 | HTR2A (0.57) | SMN1; SMN2HTR2AHMGCRTAAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059373-A1 | NOVEL PHENALKYLAMINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |