Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14334654 | 0.83 | CHRNA7 (0.36) | CTSKGAAHDAC4HDAC6CA1 | |
| SCHEMBL20958793 | 0.80 | PDE7A (0.36) | F10 | |
| SCHEMBL22859904 | 0.79 | CTSK (0.46) | CTSKGAAL3MBTL1CA1CA2 | |
| SCHEMBL28380084 | 0.79 | NFKB1 (0.38) | CTSKGAANFKB1NFKB2RELA | |
| SCHEMBL22859897 | 0.78 | CTSK (0.45) | CTSKGAAL3MBTL1NFKB1NFKB2 | |
| SCHEMBL421148 | 0.77 | CHRNA7 (0.53) | CTSKGAACA1CA2BTK | |
| SCHEMBL10153346 | 0.77 | CHRNA7 (0.53) | CTSKGAACA1CA2BTK | |
| SCHEMBL421147 | 0.77 | CHRNA7 (0.53) | CTSKGAACA1CA2BTK | |
| SCHEMBL20063738 | 0.76 | CHRNA7 (0.55) | CTSKGAACA1CA2BTK | |
| SCHEMBL31021493 | 0.76 | CHRNA7 (0.52) | CTSKGAACA1CA2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032651-A | Heterocyclic compounds | 武田药品工业株式会社 | 2020-04-17 | — | — | CN | disclosed |