Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847484 | 0.90 | L3MBTL1 (0.59) | TSHRL3MBTL1ALDH1A1GLAGAA | |
| SCHEMBL2843212 | 0.89 | TSHR (0.64) | TSHRL3MBTL1GAA | |
| SCHEMBL2843660 | 0.88 | L3MBTL1 (0.52) | TSHRL3MBTL1ALDH1A1GAA | |
| SCHEMBL2837131 | 0.88 | L3MBTL1 (0.56) | TSHRL3MBTL1ALDH1A1GLAGAA | |
| SCHEMBL2846692 | 0.88 | L3MBTL1 (0.62) | TSHRL3MBTL1ALDH1A1GLAGAA | |
| SCHEMBL2841026 | 0.87 | ALDH1A1 (0.62) | TSHRL3MBTL1ALDH1A1GLAGAA | |
| SCHEMBL2843771 | 0.87 | ALDH1A1 (0.62) | TSHRL3MBTL1ALDH1A1GLAGAA | |
| SCHEMBL2843768 | 0.87 | ALDH1A1 (0.62) | TSHRL3MBTL1ALDH1A1GLAGAA | |
| SCHEMBL13381695 | 0.86 | L3MBTL1 (0.50) | TSHRL3MBTL1ALDH1A1GAA | |
| SCHEMBL2843891 | 0.86 | L3MBTL1 (0.50) | TSHRL3MBTL1ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | claimed |
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |