SCHEMBL28376459

SCHEMBL28376459

O=C(C(Br)c1ccc([N+](=O)[O-])cc1)C(Br)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CES1 P23141 2/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 1/20 0.47
GSK3B P49841 1/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 1/20 0.47
NPC1 O15118 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
PHLPP2 Q6ZVD8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CES2 O00748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9297237 0.86 TDP1 (0.52) ALDH1A1CES1MEN1KMT2AMAPT
SCHEMBL2225077 0.86 TDP1 (0.52) ALDH1A1CES1MEN1KMT2AMAPT
SCHEMBL9298100 0.85 ALDH1A1 (0.53) ALDH1A1CES1MEN1KMT2AMAPT
SCHEMBL6407218 0.85 MAPT (0.54) ALDH1A1CES1MEN1KMT2AMAPT
SCHEMBL9298105 0.85 ALDH1A1 (0.53) ALDH1A1CES1MEN1KMT2AMAPT
SCHEMBL7475129 0.85 TSHR (0.53) ALDH1A1CES1MEN1KMT2AMAPT
SCHEMBL468217 0.81 TP53 (0.46) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL521125 0.80 SLC6A3 (0.50) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL3918014 0.80 KMT2A (0.43) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL28551178 0.79 CES1 (0.57) ALDH1A1CES1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110950781-A Novel diamine, polyamic acid, and polyimide 日产化学工业株式会社 2020-04-03 CN disclosed