Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | TP53 | P04637 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380711 | 0.86 | MAPT (0.60) | MAPTLMNATP53MAPK1POLB | |
| SCHEMBL28377569 | 0.85 | MAPT (0.58) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL28377019 | 0.81 | POLB (0.65) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL28381789 | 0.81 | RXFP1 (0.65) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL28380865 | 0.81 | MAPT (0.79) | MAPTLMNATP53RAB9APOLB | |
| SCHEMBL28360016 | 0.81 | HDAC6 (0.56) | MAPTLMNATP53NPC1USP2 | |
| SCHEMBL30448570 | 0.81 | HDAC6 (0.56) | MAPTLMNATP53NPC1USP2 | |
| SCHEMBL28377067 | 0.79 | POLB (0.62) | MAPTLMNATP53RAB9APOLB | |
| SCHEMBL28360026 | 0.79 | NPC1 (0.57) | MAPTLMNATP53NPC1USP2 | |
| SCHEMBL30448260 | 0.79 | HDAC8 (0.58) | MAPTLMNATP53NPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | claimed |
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | disclosed |