Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380711 | 0.91 | MAPT (0.60) | MAPTLMNATP53ALDH1A1KMT2A | |
| SCHEMBL28376729 | 0.85 | MAPT (0.80) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL28359894 | 0.82 | CNR2 (0.61) | LMNANPC1RAB9AHDAC1ALDH1A1 | |
| SCHEMBL30448561 | 0.82 | CNR2 (0.61) | LMNANPC1RAB9AHDAC1ALDH1A1 | |
| SCHEMBL28377299 | 0.77 | HPGD (0.57) | MAPTLMNANPC1RAB9AHDAC1 | |
| SCHEMBL2408888 | 0.76 | RAB9A (0.77) | MAPTLMNANPC1RAB9AHDAC1 | |
| SCHEMBL2621633 | 0.75 | MAPT (0.62) | MAPTLMNATP53ALDH1A1KMT2A | |
| SCHEMBL28380664 | 0.75 | BRD4 (0.65) | MAPTLMNARAB9AHDAC1ALDH1A1 | |
| SCHEMBL11717444 | 0.74 | NPC1 (0.76) | LMNANPC1RAB9AALDH1A1THRB | |
| SCHEMBL107323 | 0.74 | RAB9A (0.81) | MAPTLMNANPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | claimed |
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | disclosed |