Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381789 | 0.91 | RXFP1 (0.65) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28380865 | 0.91 | MAPT (0.79) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28377067 | 0.88 | POLB (0.62) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28377022 | 0.87 | RAB9A (0.65) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28381246 | 0.84 | MAPT (0.68) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28383660 | 0.84 | HDAC6 (0.62) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28376729 | 0.81 | MAPT (0.80) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28377747 | 0.80 | MAPT (0.67) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28381515 | 0.79 | KDM4E (0.58) | POLBRXFP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28380664 | 0.78 | BRD4 (0.65) | POLBRXFP1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | claimed |
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | disclosed |