SCHEMBL2837684

SCHEMBL2837684

O=c1[nH]c2nc[nH]c2c(=O)n1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 7/20 0.64
ADORA2A P29274 5/20 0.64
PDE4A P27815 4/20 0.58
PDE4B Q07343 4/20 0.58
PDE4C Q08493 4/20 0.58
PDE4D Q08499 4/20 0.58
ADORA3 P0DMS8 7/20 0.55
ACHE P22303 1/20 0.47
GDA Q9Y2T3 1/20 0.47
ABL1 P00519 1/20 0.43
RIN1 Q13671 1/20 0.43
TDP1 Q9NUW8 2/20 0.39
ADORA1 P30542 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TP53 P04637 2/20 0.38
HPGD P15428 2/20 0.38
PTGS1 P23219 2/20 0.38
HBB P68871 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28852667 0.82 ADORA2B (0.51) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL9574927 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL28648091 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL618977 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL28516221 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL5510062 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL447390 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL9949244 0.78 ADORA2B (0.64) ADORA2BADORA2APDE4APDE4BPDE4C
1-Methylxanthine SCHEMBL10996 0.78 ADORA2B (1.00) ADORA2BADORA2APDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL7296127 0.76 ADORA2B (0.62) ADORA2BADORA2APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3897677-A1 COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA ezCol B.V. (NL) 2021-10-27 EP claimed
US-20210275601-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2021-09-09 US claimed
US-11026981-B2 LDL-cholesterol-lowering cell extract and food supplement EZCOL B.V. (NL) 2021-06-08 US claimed
WO-2020130813-A1 COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA EZCOL B.V. (NL) 2020-06-25 WO claimed
EP-3638272-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT ezCol B.V. (NL) 2020-04-22 EP claimed
US-20200101120-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2020-04-02 US claimed
CN-110799202-A Cellular extracts and food supplements for lowering LDL-cholesterol 埃兹科尔公司 2020-02-14 CN claimed
WO-2018229223-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2018-12-20 WO claimed
JP-10175853-A None JP disclosed
US-20250302885-A1 RHODOSPIRILLUM RUBRUM CELLS THAT LOWER PLASMA CHOLESTEROL WHILE LEAVING OTHER SERUM PROTEIN LEVELS UNAFFECTED Curador (BE) 2025-10-02 US disclosed
CN-116283867-B Aza-substituted xanthine or chloro xanthine derivatives and application thereof 山西农业大学 2025-07-25 CN disclosed
CN-116283867-B Aza-substituted xanthine or chloro xanthine derivatives and application thereof 山西农业大学 2025-07-25 CN disclosed
CN-116283867-A Aza-substituted xanthine or chloro xanthine derivatives and application thereof 山西农业大学 2023-06-23 CN disclosed
CN-116283867-A Aza-substituted xanthine or chloro xanthine derivatives and application thereof 山西农业大学 2023-06-23 CN disclosed
CN-1336956-A Method for culturing algae capable of producing phototrophic pigments, highly unsaturated fatty acids or polysaccharides in high concentration MICRO GAIA CO LTD (JP) 2002-02-20 CN disclosed
US-6342377-B1 AEROBIC PROCESS COSMO RESEARCH INTITUTE (JP) 2002-01-29 US disclosed
EP-1138757-A1 METHOD OF CULTURING ALGAE CAPABLE OF PRODUCING PHOTOTROPHIC PIGMENTS, HIGHLY UNSATURATED FATTY ACIDS, OR POLYSACCHARIDES AT HIGH CONCENTRATION Micro Gaia Co., Ltd. (JP) 2001-10-04 EP disclosed
JP-2001161391-A METHOD OF MANUFACTURING CAROTENOID NIKKEN SOHONSHA CORP 2001-06-19 JP disclosed
EP-1018546-A1 MICROORGANISMS PRODUCING 5-AMINOLEVULINIC ACID AND PROCESSES FOR PRODUCING 5-AMINOLEVULINIC ACID BY USING THE SAME Cosmo Research Institute (JP) 2000-07-12 EP disclosed
JP-H10175853-A APOTOSIS INDUCING AGENT COSMO SOGO KENKYUSHO:KK 1998-06-30 JP disclosed