SCHEMBL28377435

SCHEMBL28377435

O=S(=O)(O)c1cccc(-c2ccccc2)c1C=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
PTPN6 P29350 1/20 0.44
NFE2L2 Q16236 1/20 0.41
CASP1 P29466 2/20 0.38
PELI1 Q96FA3 2/20 0.36
TRPV1 Q8NER1 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
KDM1A O60341 1/20 0.36
F10 P00742 1/20 0.35
CHAT P28329 1/20 0.35
SNCA P37840 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HDAC3 O15379 1/20 0.35
TNKS O95271 1/20 0.35
HDAC4 P56524 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29990836 1.00 PTPN1 (0.44) PTPN1PTPN6NFE2L2CASP1PELI1
(Z)-1,2-Diphenylethene SCHEMBL27449534 0.88 PTPN1 (0.47) PTPN1PTPN6CASP1PELI1TRPV1
(Z)-1,2-Diphenylethene SCHEMBL28265888 0.87 PTPN1 (0.44) PTPN1PTPN6NFE2L2CASP1PELI1
SCHEMBL15534783 0.86 PTPN1 (0.43) PTPN1PTPN6NFE2L2CASP1PELI1
SCHEMBL9346546 0.84 PTPN1 (0.38) PTPN1PTPN6NFE2L2CASP1PELI1
SCHEMBL1539831 0.83 PTPN1 (0.43) PTPN1PTPN6NFE2L2PELI1TRPV1
SCHEMBL29991128 0.83 PTPN1 (0.40) PTPN1PTPN6NFE2L2CASP1TRPV1
SCHEMBL11400872 0.80 TRPA1 (0.47) NFE2L2HDAC1HDAC6ALDH1A1MAPT
SCHEMBL11400869 0.80 TRPA1 (0.47) NFE2L2HDAC1HDAC6ALDH1A1MAPT
SCHEMBL28210865 0.80 CASP1 (0.40) CASP1HDAC6CHATSNCAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113834794-A Detection method for rapidly detecting quality of fluorescent whitening agent 浙江宏达化学制品有限公司 2021-12-24 CN claimed
CN-113736579-A Fluorescent whitening agent composition with low salt content and preparation method thereof 浙江宏达化学制品有限公司 2021-12-03 CN claimed
CN-110857418-A Novel liquid fluorescent whitening agent 山西晋光化工有限公司 2020-03-03 CN claimed
CN-113834794-A Detection method for rapidly detecting quality of fluorescent whitening agent 浙江宏达化学制品有限公司 2021-12-24 CN disclosed
CN-113736579-A Fluorescent whitening agent composition with low salt content and preparation method thereof 浙江宏达化学制品有限公司 2021-12-03 CN disclosed
CN-113638219-A Preparation method of low-temperature-resistant fluorescent whitening slurry 奥仕集团有限公司 2021-11-12 CN disclosed
CN-110857418-A Novel liquid fluorescent whitening agent 山西晋光化工有限公司 2020-03-03 CN disclosed
CN-110857418-A Novel liquid fluorescent whitening agent 山西晋光化工有限公司 2020-03-03 CN disclosed