Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27861545 | 0.76 | MAPT (0.42) | ELANEMAPTNPC1RAB9APSMB8 | |
| SCHEMBL27844360 | 0.74 | ELANE (0.44) | ELANEMAPTNPC1RAB9AALOX5 | |
| SCHEMBL1553499 | 0.73 | ELANE (0.58) | ELANEMAPTNPC1RAB9AALOX5 | |
| SCHEMBL21488100 | 0.72 | NPC1 (0.47) | ELANEMAPTNPC1RAB9AALOX5 | |
| SCHEMBL10423403 | 0.71 | MAOB (0.40) | — | |
| SCHEMBL21488211 | 0.71 | ELANE (0.46) | ELANEMAPTNPC1RAB9APSMB8 | |
| SCHEMBL1554271 | 0.71 | NPC1 (0.46) | ELANEMAPTNPC1RAB9AALOX5 | |
| SCHEMBL27844354 | 0.70 | NPC1 (0.49) | ELANEMAPTNPC1RAB9APSMB8 | |
| SCHEMBL27844356 | 0.70 | MAPT (0.42) | ELANEMAPTNPC1RAB9APSMB8 | |
| SCHEMBL28594664 | 0.69 | MAOB (0.38) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588807-B | Alkene compound containing gem-difluoromethylene and preparation method thereof | 上海大学 | 2020-04-03 | — | — | CN | disclosed |