Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21488100 | 0.86 | NPC1 (0.47) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL21488211 | 0.84 | ELANE (0.46) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL1554271 | 0.84 | NPC1 (0.46) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL5720494 | 0.81 | NPC1 (0.50) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL3913461 | 0.81 | NPC1 (0.50) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL1792867 | 0.79 | ELANE (0.58) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL23207497 | 0.78 | MAPT (0.47) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL29639834 | 0.78 | MAPT (0.47) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL34471230 | 0.76 | MAPT (0.46) | ELANENPC1RAB9AMAPTPSMB8 | |
| SCHEMBL31391574 | 0.75 | ELANE (0.41) | ELANEALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939140-A | ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1990-07-03 | — | — | US | claimed |
| US-12384787-B2 | Fused heterocyclic compounds and their use as pest control agents | PI INDUSTRIES LTD (IN) | 2025-08-12 | — | — | US | disclosed |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | SUNDANCE BIOSCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
| US-20230255906-A1 | Targeting Serpin B9 in Cancer | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2023-08-17 | — | — | US | disclosed |
| US-20220251094-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2022-08-11 | — | — | US | disclosed |
| CN-105358555-B | Condensed heterocyclic compound and pest control use thereof | 住友化学株式会社 | 2018-01-30 | — | — | CN | disclosed |
| CN-105061348-B | A kind of preparation method of 2 substituted benzene Bing oxazole compounds | 河南师范大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-105431427-B | Novel PDE 4 inhibitor | 明治制果药业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| EP-2044038-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | Cornerstone Therapeutics Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146066-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CRITICAL THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| CN-1319953-C | Method for preparing 2-trifluoro methyl benzoxazole | UNIV SHANGHAI (CN) | 2007-06-06 | — | — | CN | disclosed |
| CN-1775766-A | Method for preparing 2-trifluoro methyl benzoxazole | UNIV SHANGHAI (CN) | 2006-05-24 | — | — | CN | disclosed |
| EP-0669927-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5405938-A | Hydrogen bonding an N-heterocyclic-substituted ribose-based polymer to a double-stranded DNA to block genetic activity, to diagnose for pathogens and to aid in genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1995-04-11 | — | — | US | disclosed |
| WO-1994012517-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| EP-0357082-A2 | Silver halide photographic emulsions | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4546075-A | TETRAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, OR BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384787-B2 | Fused heterocyclic compounds and their use as pest control agents | DDT, ACHE, KEAP1 | ELANE 4257/4885NPC1 3338/4885RAB9A 29/4885 |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NLRP3, NLRP1, NOD1 | ELANE 773/4885NPC1 545/4885RAB9A 1629/4885 |
| US-20230255906-A1 | Targeting Serpin B9 in Cancer | SERPINB10, SERPINB8, SERPINE1 | ELANE 121/4885NPC1 1048/4885RAB9A 338/4885 |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | TYK2, JAK1, JAK3 | ELANE 4593/4885NPC1 4600/4885RAB9A 3465/4885 |
| US-20220251094-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | DDT, ACHE, KEAP1 | ELANE 4257/4885NPC1 3338/4885RAB9A 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.