Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553499 | 0.81 | ELANE (0.58) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13499117 | 0.80 | ELANE (0.45) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21488100 | 0.79 | NPC1 (0.47) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21488211 | 0.78 | ELANE (0.46) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1554271 | 0.78 | NPC1 (0.46) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29226418 | 0.76 | ALDH1A1 (0.44) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29226423 | 0.76 | ALDH1A1 (0.44) | ELANENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3913461 | 0.75 | NPC1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5720494 | 0.75 | NPC1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28377575 | 0.74 | ELANE (0.41) | ELANENPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102260223-A | Serial-aristeromycin compounds containing 1,3-benzodiazole and synthesis method thereof | — | 2011-11-30 | — | — | CN | disclosed |