Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 11/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379087 | 0.93 | PIM1 (0.41) | PIM1PIM3PIM2CHEK1SLC6A3 | |
| SCHEMBL28379118 | 0.87 | PIM1 (0.43) | PIM1PIM3CSF1R | |
| SCHEMBL28887709 | 0.85 | CSF1R (0.57) | CSF1R | |
| SCHEMBL28382809 | 0.80 | PIM1 (0.43) | PIM1PIM3CSF1R | |
| SCHEMBL28383473 | 0.79 | PIM1 (0.39) | PIM1PIM3PIM2CHEK1SLC6A3 | |
| SCHEMBL29033318 | 0.79 | SLC6A3 (0.44) | PIM1PIM3PIM2CHEK1SLC6A3 | |
| SCHEMBL20598602 | 0.79 | PIM1 (0.44) | PIM1PIM3PIM2CHEK1CSF1R | |
| SCHEMBL20598423 | 0.78 | PIM1 (0.46) | PIM1PIM3PIM2CSF1R | |
| SCHEMBL28383104 | 0.78 | CYP1A2 (0.58) | CSF1R | |
| SCHEMBL20597905 | 0.77 | CSF1R (0.44) | PIM1PIM3PIM2KCNH2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-A | Kinase inhibitors and methods of making and using | 里格尔药品股份有限公司 | 2020-04-17 | — | — | CN | disclosed |