Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 12/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382326 | 0.95 | PIM1 (0.40) | PIM1PIM3CHEK1SLC6A3KCNH2 | |
| SCHEMBL28382359 | 0.88 | PIM1 (0.41) | PIM1PIM3 | |
| SCHEMBL28378607 | 0.83 | CSF1R (0.51) | — | |
| SCHEMBL29033318 | 0.83 | SLC6A3 (0.44) | PIM1PIM3CHEK1SLC6A3KCNH2 | |
| SCHEMBL29033218 | 0.83 | CHEK1 (0.54) | CHEK1CCNE1CDK2 | |
| SCHEMBL28887910 | 0.82 | PIM1 (0.41) | PIM1PIM3 | |
| SCHEMBL28380085 | 0.79 | PIM1 (0.42) | PIM1PIM3CHEK1SLC6A3KCNH2 | |
| SCHEMBL29033317 | 0.78 | AKT1 (0.41) | — | |
| SCHEMBL28378694 | 0.78 | CYP1A2 (0.53) | — | |
| SCHEMBL28379245 | 0.77 | PIM1 (0.42) | PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111032642-A | Kinase inhibitors and methods of making and using | 里格尔药品股份有限公司 | 2020-04-17 | — | — | CN | disclosed |