Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528546 | 0.85 | LMNA (0.36) | MEN1KMT2ATSHRLMNACHRM2 | |
| SCHEMBL28687413 | 0.84 | LMNA (0.35) | MEN1KMT2ATSHRLMNACHRM2 | |
| SCHEMBL9463121 | 0.80 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL8634087 | 0.80 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL3340418 | 0.77 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL3339552 | 0.77 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL3342130 | 0.77 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL28513037 | 0.77 | TSHR (0.40) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL28350438 | 0.77 | MGMT (0.32) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL11806002 | 0.76 | LMNA (0.41) | TSHRLMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783205-A | Compounds for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 尼坎治疗公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113365662-A | Method of treatment | 盖纳万科学有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113226332-A | Bivalent targeting conjugates | 阿布特斯生物制药公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-110997692-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2020-04-10 | — | — | CN | disclosed |