Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.39 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206000 | 0.78 | CES1 (0.41) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL325418 | 0.77 | CES1 (0.44) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL8089101 | 0.77 | HSP90AA1 (0.45) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL5208522 | 0.76 | CES1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL5204019 | 0.76 | CES1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL1720749 | 0.75 | EGFR (0.35) | CES1CES2ALDH1A1TP53ZDHHC20 | |
| SCHEMBL29872685 | 0.75 | CES1 (0.42) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL28165600 | 0.75 | CES1 (0.42) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL28890853 | 0.75 | FAAH (0.47) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL24241989 | 0.74 | MEN1 (0.36) | CES1CES2ALDH1A1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010121042-A1 | PROCESS FOR ABSORBING AND ADSORBING OIL DEGRADATION PRODUCTS FROM LUBRICATING OILS | FLUITEC INTERNATIONAL (US) | 2010-10-21 | — | — | WO | disclosed |