Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838405 | 0.75 | CES1 (0.39) | CES2CES1ALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL1700981 | 0.72 | EGFR (0.54) | EGFRLMNAALDH1A1L3MBTL1RAB9A | |
| SCHEMBL2534565 | 0.72 | EGFR (0.54) | EGFRLMNAALDH1A1L3MBTL1RAB9A | |
| SCHEMBL24241989 | 0.67 | MEN1 (0.36) | CES2CES1ALDH1A1TP53 | |
| SCHEMBL9462903 | 0.67 | ALDH1A1 (0.57) | CES2CES1ALDH1A1TP53MAPT | |
| SCHEMBL5208649 | 0.66 | TSHR (0.36) | EGFRALDH1A1ZDHHC20ZDHHC2CNR1 | |
| SCHEMBL1916578 | 0.66 | CNR1 (0.64) | ALDH1A1CNR1CNR2 | |
| SCHEMBL17556044 | 0.66 | CNR1 (0.64) | ALDH1A1CNR1CNR2 | |
| SCHEMBL13124171 | 0.65 | EGFR (0.44) | EGFRLMNAALDH1A1L3MBTL1CNR1 | |
| SCHEMBL6364252 | 0.64 | EGFR (0.52) | EGFRLMNAALDH1A1L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678870-B2 | Processable molecularly imprinted polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-03-16 | — | — | US | claimed |
| US-20070197746-A1 | Processable molecularly imprinted polymers | THE JOHNS HOPKINS UNIVERSITY | 2007-08-23 | — | — | US | claimed |
| EP-1733211-A4 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | UNIV JOHNS HOPKINS (US) | 2007-05-30 | — | — | EP | claimed |
| EP-1733211-A1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | THE JOHNS-HOPKINS UNIVERSITY (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005103655-A1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-11-03 | — | — | WO | claimed |
| EP-1733211-B1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | UNIV JOHNS HOPKINS (US) | 2012-01-11 | — | — | EP | disclosed |
| US-7799568-B2 | Authentication of products using molecularly imprinted polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-09-21 | — | — | US | disclosed |
| US-7678870-B2 | Processable molecularly imprinted polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20080056940-A1 | Authentication Of Products Using Molecularly Imprinted Polymers | JOHNS HOPKINS UNIVERISTY | 2008-03-06 | — | — | US | disclosed |
| US-20070197746-A1 | Processable molecularly imprinted polymers | THE JOHNS HOPKINS UNIVERSITY | 2007-08-23 | — | — | US | disclosed |
| EP-1733211-A4 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | UNIV JOHNS HOPKINS (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1733211-A1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | THE JOHNS-HOPKINS UNIVERSITY (US) | 2006-12-20 | — | — | EP | disclosed |
| US-7067702-B2 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY | 2006-03-30 | — | — | US | disclosed |
| WO-2005103655-A1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005038734-A2 | AUTHENTICATION OF PRODUCTS USING MOLECULARLY IMPRINTED POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | VRK1, VRK2, DEK | EGFR 2120/4885CES2 2479/4885CES1 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.