Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841757 | 1.00 | KMT2A (0.39) | KMT2AMEN1L3MBTL1TSHRHRH3 | |
| Hydrochloric Acid SCHEMBL2842975 | 0.99 | KMT2A (0.40) | KMT2AMEN1L3MBTL1TSHRHRH3 | |
| SCHEMBL2841451 | 0.88 | SLC6A2 (0.42) | KMT2AMEN1L3MBTL1TSHRHRH3 | |
| Citric Acid SCHEMBL2840328 | 0.87 | CHRM3 (0.36) | KMT2AMEN1HSD17B10CHRM4CHRM5 | |
| SCHEMBL2840421 | 0.84 | PKM (0.34) | L3MBTL1SLC6A2SLC6A4SLC6A3NOS3 | |
| SCHEMBL2839613 | 0.81 | HRH3 (0.37) | KMT2AMEN1L3MBTL1TSHRHRH3 | |
| SCHEMBL2839108 | 0.81 | SIGMAR1 (0.36) | KMT2AMEN1L3MBTL1RAB9ADRD2 | |
| Hydrochloric Acid SCHEMBL2841722 | 0.81 | KMT2A (0.38) | KMT2AMEN1L3MBTL1TSHRHRH3 | |
| SCHEMBL2837126 | 0.80 | HRH3 (0.39) | KMT2AMEN1TSHRHRH3SLC6A2 | |
| SCHEMBL2846176 | 0.78 | MEN1 (0.38) | KMT2AMEN1L3MBTL1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141168-A1 | HETEROARYL DERIVATIVES | Nippon Shinyaku Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |