Perflexane

Perflexane

SCHEMBL28384308

C=C(C)C(=O)OCC.FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.48
TSHR P16473 4/20 0.43
ALDH1A1 P00352 7/20 0.41
MAPT P10636 3/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
GLO1 Q04760 1/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
NPSR1 Q6W5P4 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31553186 1.00 THRB (0.48) THRBTSHRALDH1A1MAPTKDM4E
SCHEMBL28507059 0.86 THRB (0.38) THRBTSHRALDH1A1MAPTKDM4E
Ammonia Solution, Strong SCHEMBL27197714 0.86 THRB (0.38) THRBTSHRALDH1A1MAPTKDM4E
SCHEMBL28381855 0.86 THRB (0.38) THRBTSHRALDH1A1MAPTKDM4E
SCHEMBL20262113 0.84 THRB (0.39) THRBTSHRALDH1A1MAPTKDM4E
Chloromethane SCHEMBL17453350 0.83 THRB (0.59) THRBTSHRALDH1A1MAPTGLO1
SCHEMBL15030 0.83
SCHEMBL19409375 0.83 THRB (0.64) THRBTSHRALDH1A1MAPTGLO1
SCHEMBL3093443 0.83 ALDH1A1 (0.43) THRBTSHRALDH1A1MAPTKDM4E
SCHEMBL1536970 0.81 TSHR (0.40) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114174362-A Fluorine-containing copolymer 大金工业株式会社 2022-03-11 CN disclosed
CN-108948939-B Multifunctional electronic protective coating composition with low dielectric constant 黑龙江泰纳科技发展股份有限公司 2020-04-10 CN disclosed