Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388205 | 0.93 | L3MBTL1 (0.44) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28387157 | 0.87 | L3MBTL1 (0.48) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28385257 | 0.86 | MEN1 (0.47) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28761848 | 0.84 | L3MBTL1 (0.48) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28384613 | 0.84 | L3MBTL1 (0.45) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28381472 | 0.84 | SCN1A (0.55) | MEN1KMT2AL3MBTL1HTTLMNA | |
| SCHEMBL28386709 | 0.84 | L3MBTL1 (0.45) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28380892 | 0.84 | L3MBTL1 (0.45) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL28385517 | 0.83 | MEN1 (0.47) | MEN1KMT2AL3MBTL1HTTTDP1 | |
| SCHEMBL27741121 | 0.81 | KMT2A (0.45) | MEN1KMT2AL3MBTL1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-111051309-A | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2020-04-21 | — | — | CN | disclosed |