Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380892 | 1.00 | L3MBTL1 (0.45) | L3MBTL1HTTMEN1KMT2ATSHR | |
| SCHEMBL28384613 | 1.00 | L3MBTL1 (0.45) | L3MBTL1HTTMEN1KMT2ATSHR | |
| SCHEMBL28387157 | 0.96 | L3MBTL1 (0.48) | L3MBTL1HTTMEN1KMT2ATSHR | |
| SCHEMBL28388205 | 0.88 | L3MBTL1 (0.44) | L3MBTL1HTTMEN1KMT2AKDM4E | |
| SCHEMBL28385257 | 0.84 | MEN1 (0.47) | L3MBTL1HTTMEN1KMT2ALMNA | |
| SCHEMBL28384602 | 0.84 | MEN1 (0.47) | L3MBTL1HTTMEN1KMT2ALMNA | |
| SCHEMBL28381472 | 0.82 | SCN1A (0.55) | L3MBTL1HTTMEN1KMT2ATSHR | |
| SCHEMBL28761848 | 0.80 | L3MBTL1 (0.48) | L3MBTL1HTTMEN1KMT2ATSHR | |
| SCHEMBL28385517 | 0.78 | MEN1 (0.47) | L3MBTL1HTTMEN1KMT2ALMNA | |
| SCHEMBL28381537 | 0.77 | LTB4R (0.41) | L3MBTL1MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-111051309-A | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2020-04-21 | — | — | CN | disclosed |