SCHEMBL28385202

SCHEMBL28385202

Cc1cc(CCCc2ccccc2)cc(C)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.56
PTGS2 P35354 3/20 0.56
IGF1R P08069 1/20 0.48
ALOX15 P16050 1/20 0.48
SIGMAR1 Q99720 2/20 0.46
TTR P02766 1/20 0.46
ALOX5 P09917 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HTR2A P28223 1/20 0.45
BCL2 P10415 1/20 0.44
BCL2L1 Q07817 1/20 0.44
MCL1 Q07820 1/20 0.44
BCL2A1 Q16548 1/20 0.44
HDAC3 O15379 1/20 0.44
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
HDAC4 P56524 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13554435 0.92 PTGS1 (0.66) PTGS1PTGS2IGF1RALOX15TTR
SCHEMBL15051455 0.90 PTGS1 (0.68) PTGS1PTGS2IGF1RALOX15ALOX5
SCHEMBL2570939 0.87 PTGS2 (0.57) PTGS1PTGS2ALOX5NPC1RAB9A
SCHEMBL8846095 0.83 PTGS2 (0.57) PTGS1PTGS2IGF1RALOX15ALOX5
SCHEMBL3688861 0.81 PTGS1 (0.53) PTGS1PTGS2ALOX5BCL2BCL2L1
SCHEMBL28386624 0.81 IGF1R (0.65) PTGS2IGF1RALOX15ALOX5HTR2A
SCHEMBL28232927 0.81 PTGS2 (0.55) PTGS1PTGS2IGF1RALOX15NPC1
SCHEMBL28683846 0.79 SMN1; SMN2 (0.49) ALOX5SMN1; SMN2NPC1RAB9ABCL2L1
SCHEMBL9480008 0.79 HMGB1 (0.55) PTGS1PTGS2TTRALOX5BCL2
SCHEMBL9182296 0.78 PTPN1 (0.45) PTGS1PTGS2IGF1RALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111004385-B Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-04-12 CN disclosed
CN-117659387-A Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-03-08 CN disclosed
CN-117178007-A Phenylether oligomers and curable thermoset compositions comprising the same 高新特殊工程塑料全球技术有限公司 2023-12-05 CN disclosed
CN-114616263-A Curing composition for toughening epoxy resins 高新特殊工程塑料全球技术有限公司 2022-06-10 CN disclosed
CN-111004385-A Poly (arylene ether) copolymers 沙特基础工业全球技术有限公司 2020-04-14 CN disclosed