Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.68 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SHBG | P04278 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570939 | 0.93 | PTGS2 (0.57) | PTGS1PTGS2SLC28A3ESR1ESR2 | |
| SCHEMBL28385202 | 0.90 | PTGS1 (0.56) | PTGS1PTGS2IGF1RALOX15ALOX5 | |
| SCHEMBL8846095 | 0.88 | PTGS2 (0.57) | PTGS1PTGS2IGF1RALOX15ESR1 | |
| SCHEMBL28232927 | 0.86 | PTGS2 (0.55) | PTGS1PTGS2IGF1RALOX15ESR1 | |
| SCHEMBL21694277 | 0.84 | PTGS1 (0.71) | PTGS1PTGS2SLC28A3ESR1ESR2 | |
| SCHEMBL3801816 | 0.83 | PTGS1 (0.68) | PTGS1PTGS2ESR1ESR2ALOX5 | |
| SCHEMBL200140 | 0.82 | NPC1 (0.63) | PTGS1PTGS2ESR1ESR2CA1 | |
| SCHEMBL2908360 | 0.82 | TNKS2 (0.53) | PTGS1PTGS2ESR1ESR2ALOX5 | |
| SCHEMBL13554435 | 0.80 | PTGS1 (0.66) | PTGS1PTGS2IGF1RALOX15ALOX5 | |
| SCHEMBL2413026 | 0.80 | PTGS2 (0.50) | PTGS1PTGS2IGF1RALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130161564-A1 | NanoStructured Additives to High-Performance Polymers for Use in Radiation Shielding, Protection Against Atomic Oxygen and in Structural Applications | International Scientific Technologies, Inc. (US) | 2013-06-27 | — | — | US | disclosed |