Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | TDP2 | O95551 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386595 | 0.93 | SRD5A2 (0.51) | SRD5A2TDP2ALDH1A1ALOX5HTT | |
| SCHEMBL398818 | 0.87 | TDP2 (0.66) | SRD5A2TDP2ALDH1A1HTTSMYD3 | |
| SCHEMBL29713338 | 0.87 | TDP2 (0.66) | SRD5A2TDP2ALDH1A1HTTSMYD3 | |
| SCHEMBL28380734 | 0.84 | KDM4E (0.54) | SRD5A2TDP2ALDH1A1ALOX5HTT | |
| SCHEMBL28387896 | 0.82 | CRBN (0.42) | SRD5A2TDP2ALDH1A1MAPTSMYD3 | |
| SCHEMBL5058746 | 0.81 | SRD5A2 (0.63) | SRD5A2TDP2ALDH1A1ALOX5HTT | |
| SCHEMBL4801160 | 0.80 | MAPT (0.56) | SRD5A2TDP2ALDH1A1ALOX5KDM4E | |
| SCHEMBL6901141 | 0.79 | SRD5A2 (0.66) | SRD5A2TDP2ALDH1A1KDM4EMAPT | |
| SCHEMBL1144991 | 0.78 | SMYD3 (0.59) | SRD5A2TDP2ALDH1A1HTTKDM4E | |
| SCHEMBL31490089 | 0.78 | BRD4 (0.54) | SRD5A2TDP2ALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111040157-A | High-barrier polyimide containing 9,10-dihydroacridine structure and preparation method and application thereof | 湖南工业大学 | 2020-04-21 | — | — | CN | disclosed |