SCHEMBL28385356

SCHEMBL28385356

C=C=C.NS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.64
PTGS2 P35354 8/20 0.60
PTGS1 P23219 7/20 0.60
CA2 P00918 9/20 0.58
CA1 P00915 8/20 0.58
CA9 Q16790 7/20 0.56
CA12 O43570 6/20 0.56
CA4 P22748 3/20 0.56
CA7 P43166 3/20 0.56
MAOA P21397 2/20 0.56
MAOB P27338 1/20 0.55
CA14 Q9ULX7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283919 0.91 SOS1 (0.75) SOS1PTGS2PTGS1CA2CA1
SCHEMBL31527705 0.91 SOS1 (0.75) SOS1PTGS2PTGS1CA2CA1
Iodide SCHEMBL28540305 0.88 SOS1 (0.72) SOS1PTGS2PTGS1CA2CA1
Hydrochloric Acid SCHEMBL29876112 0.88 SOS1 (0.72) SOS1PTGS2PTGS1CA2CA1
SCHEMBL8043459 0.88 SOS1 (0.72) SOS1PTGS2PTGS1CA2CA1
SCHEMBL1430142 0.84 CA2 (0.76) SOS1PTGS2PTGS1CA2CA1
Sulfanilamide SCHEMBL27994963 0.82 CA2 (0.77) SOS1PTGS2PTGS1CA2CA1
SCHEMBL27510169 0.78 SOS1 (1.00) SOS1PTGS2PTGS1CA2CA1
Acrylic Acid SCHEMBL28634409 0.78 CA1 (0.57) SOS1PTGS2PTGS1CA2CA1
SCHEMBL202948 0.77 CA2 (0.81) CA2CA1CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452143-B Method for mildly and efficiently synthesizing 1, 3-disulfide derivative 西南民族大学 2020-04-28 CN disclosed