Acrylic Acid

Acrylic Acid

SCHEMBL28634409

C=CC(=O)O.NS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 11/20 0.57
CA2 P00918 11/20 0.57
CA9 Q16790 10/20 0.57
CA12 O43570 7/20 0.57
CA4 P22748 4/20 0.57
CA7 P43166 3/20 0.57
MAOA P21397 1/20 0.57
SOS1 Q07889 1/20 0.55
CA14 Q9ULX7 2/20 0.53
PTGS2 P35354 5/20 0.51
PTGS1 P23219 4/20 0.51
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CYP2C19 P33261 1/20 0.50
CA5A P35218 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283919 0.82 SOS1 (0.75) CA1CA2CA9CA12CA4
Acrylic Acid Methyl Ester SCHEMBL29076835 0.82 CA1 (0.54) CA1CA2CA9CA12CA4
SCHEMBL31527705 0.82 SOS1 (0.75) CA1CA2CA9CA12CA4
SCHEMBL8043459 0.80 SOS1 (0.72) CA1CA2CA9CA12CA4
Iodide SCHEMBL28540305 0.80 SOS1 (0.72) CA1CA2CA9CA12CA4
Hydrochloric Acid SCHEMBL29876112 0.80 SOS1 (0.72) CA1CA2CA9CA12CA4
Trifluoroacetic Acid SCHEMBL27865608 0.79 CA2 (0.59) CA1CA2CA9CA12CA4
SCHEMBL28385356 0.78 SOS1 (0.64) CA1CA2CA9CA12CA4
Acrylic Acid SCHEMBL30115050 0.77 CA1 (0.50) CA1CA2CA9CA12CA4
SCHEMBL1430142 0.76 CA2 (0.76) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113461632-B Preparation method of methyl 3- ((4-fluorophenyl) sulfonyl) -4-hydroxy-2-methylthiazolidine-2-carboxylate 上海应用技术大学 2022-12-16 CN disclosed
CN-113461632-A Preparation method of methyl 3- ((4-fluorophenyl) sulfonyl) -4-hydroxy-2-methylthiazolidine-2-carboxylate 上海应用技术大学 2021-10-01 CN disclosed