Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | AGXT | P21549 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768643 | 0.85 | IDO1 (0.71) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL7547832 | 0.81 | CHRM2 (0.62) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL12093572 | 0.80 | IDO1 (0.65) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL28382952 | 0.79 | IDO1 (0.68) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL6205291 | 0.79 | IDO1 (0.62) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL6205292 | 0.79 | IDO1 (0.62) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL11021612 | 0.79 | IDO1 (0.62) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL3156159 | 0.79 | IDO1 (0.62) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL13788789 | 0.79 | IDO1 (0.62) | CHRM2CHRM1CHRM3IDO1AGXT | |
| SCHEMBL14001454 | 0.79 | CHRM2 (0.59) | CHRM2CHRM1CHRM3IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |