Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.71 |
| ▸ | AGXT | P21549 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 7/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12093572 | 0.90 | IDO1 (0.65) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL6205292 | 0.88 | IDO1 (0.62) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL28382952 | 0.88 | IDO1 (0.68) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL6205291 | 0.88 | IDO1 (0.62) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL11021612 | 0.88 | IDO1 (0.62) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL3156159 | 0.88 | IDO1 (0.62) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL31264 | 0.87 | IDO1 (0.71) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL19049283 | 0.87 | IDO1 (0.61) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL2091873 | 0.87 | IDO1 (0.61) | IDO1AGXTMAOBTAAR1CHRM2 | |
| SCHEMBL18997045 | 0.85 | IDO1 (0.59) | IDO1AGXTMAOBTAAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368218-A | Method for preparing 4-diaryl methyl substituted phenol compound | 湖南理工学院 | 2022-11-22 | — | — | CN | disclosed |
| CN-114605299-A | Electrophilic trifluoromethyl selenium-based reagent, preparation method and application thereof | 浙江师范大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-110475478-A | The method of the process economics of ingredient and its production and purposes in cutting/classification separating plant starting material | DIETZ MAX | 2019-11-19 | — | — | CN | disclosed |
| US-8389544-B2 | Isoquinolone compounds as subtype-selective agonists for melatonin receptors MT1 and MT2 | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-03-05 | — | — | US | disclosed |
| US-20100317691-A1 | ISOQUINOLONE COMPOUNDS AS SUBTYPE-SELECTIVE AGONISTS FOR MELATONIN RECEPTORS MT1 AND MT2 | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-12-16 | — | — | US | disclosed |
| WO-2008092292-A1 | ISOQUINOLONE COMPOUNDS AS SUBTYPE-SELECTIVE AGONISTS FOR MELATONIN RECEPTORS MT1 AND MT2 | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-08-07 | — | — | WO | disclosed |
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| US-6172117-B1 | APPLYING THIOCYANATOALKYL QUATERNARY AMMONIUM SALTS TO WOOD | AKZO NOBEL N.V. (NL) | 2001-01-09 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999043212-A2 | WOOD PRESERVATIVES | AKZO NOBEL N.V. (NL) | 1999-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317691-A1 | ISOQUINOLONE COMPOUNDS AS SUBTYPE-SELECTIVE AGONISTS FOR MELATONIN RECEPTORS MT1 AND MT2 | MTNR1A, MTNR1B, MC2R | IDO1 340/4885AGXT 3547/4885MAOB 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.