Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.48 |
| ▸ | USP20 | Q9Y2K6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885417 | 1.00 | NSD2 (0.48) | NSD2AS3MTUSP20KDM4EALDH1A1 | |
| SCHEMBL25229990 | 0.88 | NSD2 (0.61) | NSD2AS3MTKDM4EALDH1A1MAPT | |
| SCHEMBL30052735 | 0.88 | NSD2 (0.61) | NSD2AS3MTKDM4EALDH1A1MAPT | |
| SCHEMBL982356 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL10097345 | 0.80 | MAOA (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL5857036 | 0.80 | PFKFB1 (0.67) | NSD2AS3MTKDM4EALDH1A1MAPT | |
| SCHEMBL23676484 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL23885618 | 0.79 | USP20 (0.51) | NSD2AS3MTUSP20KDM4EALDH1A1 | |
| SCHEMBL12334854 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL23885584 | 0.78 | PLA2G1B (0.46) | NSD2AS3MTUSP20KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |