Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070698 | 0.88 | CYP4F2 (0.42) | CYP4F2CYP4A11PPARGPPARAMEN1 | |
| SCHEMBL6483485 | 0.81 | CYP4F2 (0.34) | CYP4F2CYP4A11 | |
| SCHEMBL30467053 | 0.80 | CYP4F2 (0.34) | CYP4F2CYP4A11PPARGPPARACYP3A4 | |
| SCHEMBL20301952 | 0.80 | CYP4F2 (0.34) | CYP4F2CYP4A11PPARGPPARACYP3A4 | |
| SCHEMBL26636791 | 0.78 | ALDH1A1 (0.38) | CYP4F2CYP4A11PPARGPPARACYP3A4 | |
| SCHEMBL30643687 | 0.76 | RAB9A (0.38) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL31601511 | 0.76 | PPARG (0.34) | CYP4F2CYP4A11PPARGCYP3A4CYP1A2 | |
| SCHEMBL28386653 | 0.76 | CYP4F2 (0.32) | CYP4F2CYP4A11PPARGPPARACYP3A4 | |
| SCHEMBL23301466 | 0.75 | CYP4F2 (0.37) | CYP4F2CYP4A11CYP3A4KDM4EMEN1 | |
| SCHEMBL16433688 | 0.74 | MAPK1 (0.47) | CYP3A4KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914254-A | Azole-substituted pyridine compound | 大正制药株式会社 | 2020-03-24 | — | — | CN | disclosed |