Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838180 | 0.88 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10640451 | 0.87 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL17158253 | 0.84 | ALDH1A1 (0.55) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL16039148 | 0.84 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL16039147 | 0.84 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10681970 | 0.83 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10681979 | 0.83 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10495302 | 0.83 | ALDH1A1 (0.70) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10641570 | 0.82 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL10555513 | 0.81 | SMN1; SMN2 (0.62) | MEN1KMT2ASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501110-B | Fumarate prodrugs and their use in the treatment of various diseases | 阿尔克梅斯制药爱尔兰有限公司 | 2020-05-05 | — | — | CN | disclosed |