Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641570 | 0.90 | MEN1 (0.71) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL28386372 | 0.87 | MEN1 (0.66) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL17158253 | 0.83 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL10676222 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL9674431 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL28801777 | 0.81 | ALDH1A1 (0.64) | KMT2AALDH1A1LMNAHPGDTSHR | |
| SCHEMBL10677970 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL9674644 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL9672977 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL10680557 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250725-A1 | 1,4-Dihydropyridine derivatives, processes for their preparation and medicaments containing them | HEUMANN PHARMA GMBH & CO (DE) | 1988-01-07 | — | — | EP | disclosed |