Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899889 | 0.85 | SLC22A12 (0.74) | SLC22A12KDM4ETDP1SLC22A6SLC22A11 | |
| SCHEMBL28388162 | 0.82 | SLC22A12 (0.54) | SLC22A12KDM4ETDP1CNR2MAPT | |
| SCHEMBL28383517 | 0.73 | SLC22A12 (0.46) | SLC22A12KDM4EXDH | |
| SCHEMBL14919143 | 0.72 | SLC22A12 (0.74) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL9987685 | 0.71 | SLC22A12 (0.75) | SLC22A12SLC22A6SLC22A11MAPTABCG2 | |
| SCHEMBL18105414 | 0.71 | SLC22A12 (0.76) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL9994198 | 0.70 | SLC22A12 (0.49) | SLC22A12CNR2 | |
| SCHEMBL17899864 | 0.69 | SLC22A12 (0.75) | SLC22A12KDM4ETDP1MAPTPPARA | |
| SCHEMBL28856524 | 0.69 | SLC22A12 (0.44) | SLC22A12SLC22A6SLC22A11MAPTABCG2 | |
| SCHEMBL17899890 | 0.69 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |