Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386432 | 0.73 | SLC22A12 (0.53) | SLC22A12XDHKDM4E | |
| SCHEMBL28387500 | 0.73 | SLC22A12 (0.42) | SLC22A12MCL1XDHCA1CA2 | |
| SCHEMBL28063135 | 0.73 | MCL1 (0.46) | SLC22A12MCL1XDHCA1CA2 | |
| SCHEMBL11763563 | 0.72 | LMNA (0.44) | — | |
| SCHEMBL9493141 | 0.71 | GAA (0.49) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3631419 | 0.71 | WDR5 (0.44) | SLC22A12KDM4E | |
| SCHEMBL28384020 | 0.71 | IMPDH2 (0.51) | SLC22A12MCL1CA1CA2KDM4E | |
| SCHEMBL28388485 | 0.70 | MCL1 (0.46) | SLC22A12MCL1XDHCA1CA2 | |
| SCHEMBL28387514 | 0.69 | SLC22A12 (0.67) | SLC22A12CA1CA2HTR2C | |
| SCHEMBL13170778 | 0.68 | CA1 (0.55) | MCL1CA1CA2ALOX15GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |