Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899864 | 0.85 | SLC22A12 (0.75) | SLC22A12KDM4ETDP1ALDH1A1HSD17B10 | |
| SCHEMBL28386432 | 0.82 | SLC22A12 (0.53) | SLC22A12KDM4ETDP1CNR2PPARA | |
| SCHEMBL28384020 | 0.74 | IMPDH2 (0.51) | SLC22A12KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL860254 | 0.72 | PPARA (0.40) | KDM4EALDH1A1HSD17B10FBP1PPARA | |
| SCHEMBL9037321 | 0.71 | TSHR (0.46) | SLC22A12HSD17B10FBP1PPARAPPARG | |
| SCHEMBL9035224 | 0.71 | TSHR (0.46) | HSD17B10CNR2FBP1PPARAPPARG | |
| SCHEMBL17899873 | 0.70 | SLC22A12 (1.00) | SLC22A12KDM4EALDH1A1HSD17B10PPARA | |
| SCHEMBL4431085 | 0.70 | FBP1 (0.46) | KDM4EALDH1A1HSD17B10FBP1PPARA | |
| SCHEMBL17899889 | 0.70 | SLC22A12 (0.74) | SLC22A12KDM4ETDP1MAPT | |
| SCHEMBL7571218 | 0.69 | CDC25B (0.50) | KDM4ETDP1ALDH1A1HSD17B10XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |