SCHEMBL28387643

SCHEMBL28387643

CC(CCO[SiH2])OCCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TSHR P16473 1/20 0.36
IDO1 P14902 1/20 0.35
SIGMAR1 Q99720 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657672 0.83 SIGMAR1 (0.37) CA1CA2CA9TSHRIDO1
SCHEMBL1997775 0.81 TDP1 (0.47) CA1CA2CA9TSHRIDO1
SCHEMBL14118700 0.80 SIGMAR1 (0.48) SIGMAR1
SCHEMBL18473626 0.79 PPARG (0.47) SIGMAR1
SCHEMBL13901956 0.78 CA1 (0.40) CA1CA2CA9IDO1SIGMAR1
SCHEMBL29598845 0.77 TRPA1 (0.46) CA1CA2CA9TSHRIDO1
SCHEMBL11022222 0.77 CA1 (0.43) CA1CA2CA9TSHRIDO1
SCHEMBL92354 0.75 CA1 (0.44) CA1CA2CA9TSHRIDO1
SCHEMBL4449191 0.75 CA1 (0.44) CA1CA2CA9TSHRIDO1
SCHEMBL6883398 0.74 TDP1 (0.47) TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422936-B Pneumatic tire 固特异轮胎和橡胶公司 2022-03-01 CN disclosed
CN-110408093-B Rubber composition and pneumatic tire 固特异轮胎和橡胶公司 2022-01-18 CN disclosed
CN-113667194-A Pneumatic tire 固特异轮胎和橡胶公司 2021-11-19 CN disclosed
CN-109422930-B Pneumatic tire 固特异轮胎和橡胶公司 2021-03-12 CN disclosed
CN-109422942-B Pneumatic tire 固特异轮胎和橡胶公司 2021-03-09 CN disclosed
CN-111647206-A Pneumatic tire 固特异轮胎和橡胶公司 2020-09-11 CN disclosed
CN-110894314-A Resin modified oil-extended rubber 固特异轮胎和橡胶公司 2020-03-20 CN disclosed