SCHEMBL28387697

SCHEMBL28387697

COC(=O)C(=O)c1ccc(Oc2ccc3ncccc3c2)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
SCN9A Q15858 1/20 0.48
HTT P42858 2/20 0.48
ALOX15 P16050 1/20 0.48
NPC1 O15118 4/20 0.46
RAB9A P51151 3/20 0.46
CYP3A4 P08684 2/20 0.44
PPARG P37231 1/20 0.44
DOT1L Q8TEK3 1/20 0.43
MET P08581 3/20 0.43
SRC P12931 3/20 0.43
KDR P35968 2/20 0.43
AXL P30530 2/20 0.43
KIT P10721 1/20 0.43
FGFR2 P21802 1/20 0.43
FLT3 P36888 1/20 0.43
MST1R Q04912 1/20 0.43
PLK1 P53350 1/20 0.42
ABL1 P00519 2/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22407043 0.85 ALDH1A1 (0.52) ALDH1A1SCN9AHTTALOX15NPC1
SCHEMBL22406920 0.84 PARG (0.47) SCN9AHTTNPC1RAB9AMEN1
SCHEMBL22407111 0.78 KMO (0.48) ALDH1A1SCN9ARAB9AKDRMAPT
SCHEMBL22407053 0.77 MAPT (0.49) ALDH1A1HTTRAB9AKDRMEN1
SCHEMBL29380080 0.77 FLT1 (0.48) ALDH1A1RAB9AKDRPOLBMAPT
SCHEMBL22406946 0.77 FLT1 (0.48) ALDH1A1RAB9AKDRPOLBMAPT
SCHEMBL22406919 0.76 KMO (0.43) ALDH1A1RAB9ACYP3A4KDRABL1
SCHEMBL9043714 0.76 PPARG (0.51) ALDH1A1HTTNPC1RAB9APPARG
SCHEMBL20558423 0.76 ALDH1A1 (0.61) ALDH1A1SCN9AHTTALOX15NPC1
SCHEMBL22407007 0.75 PPARA (0.43) SCN9APPARGBRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032631-B Azole derivative, intermediate compound, process for producing azole derivative, agricultural and horticultural chemical, and industrial material protective agent 株式会社吴羽 2021-05-07 CN disclosed
CN-111032631-A Azole derivative, intermediate compound, process for producing azole derivative, agricultural and horticultural chemical, and industrial material protective agent 株式会社吴羽 2020-04-17 CN disclosed