Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273589 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL29681880 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL14037701 | 0.79 | SRC (0.44) | ALDH1A1TSHRKDM4ECYP2A6HPGD | |
| SCHEMBL10994369 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL24281984 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL12433186 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL20865908 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1TRIM24HPGD | |
| SCHEMBL29953591 | 0.78 | KDM4E (0.57) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL20283367 | 0.78 | PRKCI (0.50) | ALDH1A1TSHRKDM4EPTGS2RAB9A | |
| SCHEMBL29954398 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1TRIM24HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |