Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.47 |
| ▸ | ABAT | P80404 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15982258 | 1.00 | KDM4E (0.57) | KDM4EPTGS2RAB9AAPPALDH1A1 | |
| SCHEMBL29953163 | 0.84 | KDM4E (0.57) | KDM4EPTGS2RAB9AAPPALDH1A1 | |
| SCHEMBL29681880 | 0.81 | ALDH1A1 (0.42) | KDM4EPTGS2RAB9AAPPALDH1A1 | |
| SCHEMBL7273589 | 0.81 | ALDH1A1 (0.42) | KDM4EPTGS2RAB9AAPPALDH1A1 | |
| SCHEMBL29953797 | 0.79 | RAB9A (0.62) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL9834769 | 0.78 | KDM4E (0.50) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL10994369 | 0.78 | ALDH1A1 (0.44) | KDM4EPTGS2RAB9AAPPALDH1A1 | |
| SCHEMBL28387828 | 0.78 | ALDH1A1 (0.39) | KDM4EPTGS2RAB9AAPPALDH1A1 | |
| SCHEMBL13252561 | 0.77 | APP (0.73) | APP | |
| SCHEMBL24281984 | 0.76 | ALDH1A1 (0.38) | KDM4EPTGS2RAB9AAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |