Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388793 | 0.94 | PIM1 (0.39) | GAAL3MBTL1PIM1PIM2TDP1 | |
| SCHEMBL28383503 | 0.89 | TTK (0.40) | GAATDP1TSHRSMN1; SMN2PIK3CD | |
| SCHEMBL28382505 | 0.89 | MTOR (0.40) | GAAL3MBTL1EGFRERBB3TSHR | |
| SCHEMBL16514768 | 0.88 | ERBB3 (0.42) | PIM1PIM2EGFRERBB3SMN1; SMN2 | |
| SCHEMBL28388501 | 0.87 | TGFBR1 (0.40) | GAATDP1TSHRSMN1; SMN2PIK3CD | |
| SCHEMBL28388186 | 0.87 | TTK (0.46) | GAAL3MBTL1EGFRERBB3SMN1; SMN2 | |
| SCHEMBL28386152 | 0.87 | ERBB3 (0.36) | GAAL3MBTL1TDP1EGFRERBB3 | |
| SCHEMBL16822831 | 0.85 | AIMP2 (0.39) | PIM1PIM2EGFRERBB3SMN1; SMN2 | |
| SCHEMBL28387213 | 0.83 | MAPK1 (0.44) | GAAPOLBTSHRSMN1; SMN2PIK3CD | |
| SCHEMBL16514223 | 0.82 | ERBB3 (0.42) | PIM1PIM2EGFRERBB3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | claimed |
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |