Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386152 | 0.89 | ERBB3 (0.36) | TDP1PIK3CDPIK3C2BMTORPIK3CG | |
| SCHEMBL28383503 | 0.89 | TTK (0.40) | TDP1PIK3CDPIK3C2BMTORPIK3CG | |
| SCHEMBL29848007 | 0.88 | JAK2 (0.44) | TGFBR1CCNT1CDK9MKNK2EPHB4 | |
| SCHEMBL16515085 | 0.88 | JAK2 (0.44) | TGFBR1CCNT1CDK9MKNK2EPHB4 | |
| SCHEMBL28382505 | 0.88 | MTOR (0.40) | MTORPIK3CGALDH1A1SCN9ATSHR | |
| SCHEMBL28388156 | 0.87 | GAA (0.38) | TDP1PIK3CDPIK3C2BMTORPIK3CG | |
| SCHEMBL28388793 | 0.87 | PIM1 (0.39) | TDP1PIK3CDPIK3C2BMTORPIK3CG | |
| SCHEMBL28388525 | 0.87 | TTK (0.47) | TGFBR1TDP1SCN9ASMN1; SMN2SCN5A | |
| SCHEMBL16514000 | 0.85 | AIMP2 (0.40) | MTORCCNT1CDK9 | |
| SCHEMBL29847728 | 0.85 | AIMP2 (0.40) | MTORCCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | claimed |
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |