SCHEMBL28388181

SCHEMBL28388181

CC(C)c1cc(I)cc2cc3ccccc3cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRB1 P18505 1/20 0.44
UGT2B7 P16662 1/20 0.36
NQO1 P15559 1/20 0.34
CYP2A6 P11509 3/20 0.33
HTR2C P28335 2/20 0.33
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2B P41595 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 2/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21758895 0.85 GABRA1 (0.47) GABRA1GABRB2GABRB1UGT2B7CYP2A6
SCHEMBL11739257 0.76 CYP1A2 (0.43) GABRA1GABRB2GABRB1UGT2B7NQO1
SCHEMBL21758854 0.74 GABRA1 (0.44) GABRA1GABRB2GABRB1CYP2A6HTR2B
SCHEMBL28386866 0.72 NQO1 (0.35) NQO1CYP2A6TDP1HSD17B10KDM4E
SCHEMBL29387216 0.70 UGT2B7 (0.50) GABRA1GABRB2GABRB1UGT2B7CYP2A6
SCHEMBL29714137 0.70 UGT2B7 (0.42) GABRA1GABRB2GABRB1UGT2B7CYP2A6
SCHEMBL11745542 0.69 GABRA1 (0.48) GABRA1GABRB2GABRB1UGT2B7HTR2C
SCHEMBL9858819 0.68 ALDH1A1 (0.41) UGT2B7NQO1CYP2A6HTR2CHTR2A
SCHEMBL28354012 0.68 KDM4E (0.43) KDM4EALDH1A1
SCHEMBL24618446 0.66 UGT2B7 (0.42) GABRA1GABRB2GABRB1UGT2B7CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110896635-B Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2023-11-03 CN disclosed
CN-110896635-A Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-03-20 CN disclosed