Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GRN | P28799 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 11/20 | 0.35 |
| ▸ | CA2 | P00918 | 11/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 4/20 | 0.33 |
| ▸ | CA5A | P35218 | 4/20 | 0.33 |
| ▸ | CA7 | P43166 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 3/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22656980 | 0.98 | KDM4E (0.50) | KDM4EGRNSORT1PHGDHCA1 | |
| SCHEMBL12967530 | 0.82 | GRN (0.51) | KDM4EGRNSORT1PHGDHCA1 | |
| SCHEMBL20743166 | 0.81 | KDM4E (0.33) | KDM4EGRNSORT1PHGDHCA1 | |
| SCHEMBL19508023 | 0.80 | ALDH1A1 (0.40) | KDM4ECA1CA2CA9CA12 | |
| SCHEMBL18029745 | 0.79 | CA12 (0.33) | KDM4EGRNSORT1PHGDHCA1 | |
| SCHEMBL12967531 | 0.79 | GRN (0.49) | KDM4EGRNSORT1PHGDHCA1 | |
| SCHEMBL23328665 | 0.78 | CA12 (0.41) | KDM4ECA1CA2CA9CA12 | |
| SCHEMBL20757925 | 0.76 | CA12 (0.43) | KDM4ECA1CA2CA9CA12 | |
| SCHEMBL18007604 | 0.76 | LMNA (0.46) | KDM4ECA1CA2CA9CA12 | |
| SCHEMBL20760989 | 0.75 | CA12 (0.32) | PHGDHCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-111132974-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111093773-A | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors | 英夫拉索姆有限公司 | 2020-05-01 | — | — | CN | disclosed |