Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30529023 | 1.00 | CCR1 (0.45) | CCR1ENPP2PTGDR2GPR119MAP4K4 | |
| SCHEMBL28388289 | 1.00 | CCR1 (0.45) | CCR1ENPP2PTGDR2GPR119MAP4K4 | |
| SCHEMBL377605 | 0.85 | GPR119 (0.43) | CCR1ENPP2PTGDR2GPR119MAP4K4 | |
| SCHEMBL6912757 | 0.85 | GPR119 (0.47) | GPR119MAP4K4HDAC1 | |
| SCHEMBL20788244 | 0.84 | CCR1 (0.47) | CCR1ENPP2PTGDR2MGLL | |
| SCHEMBL20788251 | 0.84 | CCR1 (0.47) | CCR1ENPP2PTGDR2MGLL | |
| SCHEMBL20788464 | 0.82 | VEGFA (0.53) | GPR119MGLL | |
| SCHEMBL3664004 | 0.78 | MGLL (0.49) | CCR1PTGDR2GPR119MGLL | |
| SCHEMBL7968974 | 0.78 | MGLL (0.49) | CCR1PTGDR2GPR119MGLL | |
| SCHEMBL3664002 | 0.78 | MGLL (0.49) | CCR1PTGDR2GPR119MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094278-B | Diphenyl derivative and use thereof | 诺华股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-111094278-A | Diphenyl derivatives and their use | 诺华股份有限公司 | 2020-05-01 | — | — | CN | disclosed |