Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011749 | 0.80 | RAB9A (0.47) | RAB9ACYP2C19CTSCTAAR1SMN1; SMN2 | |
| SCHEMBL12262584 | 0.77 | CYP2C19 (0.48) | RAB9ACYP2C19CTSCTAAR1SMN1; SMN2 | |
| SCHEMBL12262043 | 0.77 | CYP2C19 (0.48) | RAB9ACYP2C19CTSCTAAR1SMN1; SMN2 | |
| SCHEMBL1425381 | 0.77 | CYP2C19 (0.48) | RAB9ACYP2C19CTSCTAAR1SMN1; SMN2 | |
| SCHEMBL657170 | 0.76 | CYP2C19 (0.55) | RAB9ACYP2C19CTSCTAAR1 | |
| SCHEMBL9326082 | 0.74 | CYP2C19 (0.46) | RAB9ACYP2C19CTSCTAAR1SMN1; SMN2 | |
| SCHEMBL1425401 | 0.73 | — | — | |
| SCHEMBL6634048 | 0.73 | — | — | |
| SCHEMBL6638026 | 0.73 | — | — | |
| SCHEMBL2753684 | 0.72 | CYP2C19 (0.44) | RAB9ACYP2C19CTSCTAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072597-B | Piperine derivative and preparation method and application thereof | 四川大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-111072597-A | Piperine derivative and preparation method and application thereof | 四川大学 | 2020-04-28 | — | — | CN | disclosed |