Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589282 | 0.80 | CYP17A1 (0.40) | PYCR1LMNACYP3A4CYP2C19KMT2A | |
| SCHEMBL1456006 | 0.80 | ALDH1A1 (0.38) | LMNAALDH1A1CYP1A2ALOX15CYP2C19 | |
| SCHEMBL11480902 | 0.78 | CYP2C9 (0.43) | PYCR1ALDH1A1CYP3A4KIF11SMN1; SMN2 | |
| SCHEMBL11486850 | 0.77 | ALDH1A1 (0.33) | PYCR1ALDH1A1TP53MAPK1 | |
| SCHEMBL11478446 | 0.77 | MEN1 (0.42) | LMNANPSR1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL11483248 | 0.76 | NPC1 (0.38) | CYP3A4 | |
| SCHEMBL11486048 | 0.74 | NPC1 (0.51) | ALDH1A1NPSR1 | |
| SCHEMBL11492433 | 0.74 | LTA4H (0.44) | NR1H2NOS3NOS1NOS2MEN1 | |
| SCHEMBL11480978 | 0.73 | MEN1 (0.39) | LMNAALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL11480174 | 0.73 | MAPT (0.38) | PYCR1ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138422-B | Medicine for preventing and treating lupus erythematosus and preparation method thereof | 牡丹江医学院 | 2020-11-17 | — | — | CN | disclosed |
| CN-111138422-A | Medicine for preventing and treating lupus erythematosus and preparation method thereof | 牡丹江医学院 | 2020-05-12 | — | — | CN | disclosed |