Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390365 | 1.00 | RAB9A (0.74) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL12443128 | 0.91 | SMN1; SMN2 (0.79) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28888709 | 0.89 | KMT2A (0.93) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28389907 | 0.89 | MAPT (0.93) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28393986 | 0.89 | MAPT (0.93) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28395587 | 0.89 | MAPT (0.72) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28395216 | 0.89 | MAPT (0.72) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28390518 | 0.89 | KMT2A (0.93) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28392610 | 0.88 | MAPT (0.71) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28392611 | 0.88 | MAPT (0.71) | RAB9AKMT2AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116464-B | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2022-09-13 | — | — | CN | claimed |
| CN-111116464-A | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2020-05-08 | — | — | CN | claimed |
| CN-111116464-B | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-111116464-A | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2020-05-08 | — | — | CN | disclosed |