Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.93 |
| ▸ | RECQL | P46063 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.73 |
| ▸ | POLB | P06746 | 7/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.73 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.73 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | NT5E | P21589 | 1/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393986 | 1.00 | MAPT (0.93) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL12443129 | 0.91 | SMN1; SMN2 (0.89) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28390365 | 0.89 | RAB9A (0.74) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28390366 | 0.89 | RAB9A (0.74) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28395216 | 0.88 | MAPT (0.72) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28390518 | 0.88 | KMT2A (0.93) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28395587 | 0.88 | MAPT (0.72) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28888709 | 0.88 | KMT2A (0.93) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28393332 | 0.87 | MAPT (0.75) | MAPTRECQLSMN1; SMN2KMT2APOLB | |
| SCHEMBL28392611 | 0.87 | MAPT (0.71) | MAPTRECQLSMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116464-B | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2022-09-13 | — | — | CN | claimed |
| CN-111116464-A | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2020-05-08 | — | — | CN | claimed |
| CN-111116464-B | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-111116464-A | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2020-05-08 | — | — | CN | disclosed |